The FXS Combi is an advancement of the proven FXS platform for syringes and features flexible and quickly exchangeable format parts for diverse packaging types. “To fulfil our customers´ demands for higher flexibility, for a more compact footprint and for extended fields of application, we transferred the successful FXS concept to further packaging types,” explained Klaus Ullherr, senior product manager at Bosch Packaging Technology. The ability to process pre-sterilized syringes as well as vials and cartridges on a single machine has led to enthusiasm worldwide. The FXS Combi has already been manufactured for customers in Italy, India, South Korea, Indonesia, Turkey and even Australia.
Individual adaptation to different requirements
Depending on the configuration, the FXS Combi developed at the Crailsheim site can be individually adapted to the various needs of the customers. In combination with the fully automatic or manual tub and bag opener ABO, ATO, MBO or MTO for nested syringes, vials and cartridges, the reliable processing of packaging materials is guaranteed. The FXS Combi also features an integrated capping station for vials and cartridges. In the monobloc solution, the capping of the containers takes place directly after the stopper insertion. This ensures highest pharmaceutical safety, as the container are being closed immediately after filling.
The FXS Combi, which won the internationally renowned “Red Dot Award” in the category product design in 2015, also impresses with its different layouts. “In addition to the linear solution, we also offer an U-shape and monobloc layout. This allows us to adapt the machine concept to the customers´ available spaces and simplifies the combination with different barrier systems,” says Ullherr.
Advantages: Flexibility as well as space and cost savings
This machine concept offers advantages particularly for research and development, as well as for clinical studies. Instead of the usual three machines, a single one will suffice to fill and close vials, syringes and cartridges. The packaging type for a new drug has often not yet been defined at an early development stage. Hence, the combination of the three most common packaging types in one platform offers pharmaceutical companies a much higher flexibility in matching medications to the appropriate packaging type.
Large-scale production machines are generally in operation almost every day. However, machines for small-batch production are used a lot less frequently. This results in greater efforts for the machine operators, since they need to adapt to each machine all over again. Combination machines can provide a remedy, as they require less operator training. Furthermore, investments pay off faster, because the machine is operated more frequently. Moreover, it reduces infrastructure and running costs, while saving space at the same time.
Ullherr is especially proud of the latest innovations of the FXS Combi: “The filling machine, which used to have two or five positions depending on the output and container, is now also available with ten positions, which can significantly increase the output quantity. In addition, our team has succeeded in developing a new concept with which cartridges can be filled with mixing balls on the FXS Combi.” This innovation is very important, for example in the filling of insulin suspensions. The mixing balls are used to disperse the liquid and thus achieve homogenization of the content.
Senior Product Manager Syringes
Phone: +49 7951 402517