Syntegon’s Slide Gate Technology Improves Capsule Filling Performance

Although Syntegon’s tamping-style capsule filling machines have set the standard for precision and durability in capsule filling for decades, that does not mean we rest on our laurels. At Syntegon, we tirelessly pursue innovations that make our industry leading equipment even better.  One of the most important of those innovations to come out of Syntegon’s Waiblingen, Germany facility in recent years is slide gate technology for capsule fillers. …more


Syntegon’s Pilot Scale High-Shear Mixer and Fluid Bed

Developing a pharmaceutical product within a Research and Development Lab can be a very expensive and time-consuming process for OSD manufacturers. Once a stable product has been developed within the lab setting, scaling up to pilot production can prove even more daunting for scientists. Pilot-scale machines provide pharmaceutical companies the tools to better understand a manufacturing process that was successful at lab scale, while also allowing for batches at less than production scale, where design changes can still be easily executed at less cost. Syntegon offers …more


How do I get my materials into an Isolator?

Fill/finish lines surrounded by RABS and/or Isolators come with many benefits, but one of the initial challenges is determining how to transfer commodities, fluid paths, tools or drug product itself into the closed ISO 5 space. Have no fear, Syntegon’s experts are here! Join Matthias Angelmaier and Dr. Laura Moody on Wednesday, May 12th at 10am CDT for the final chapter in Syntegon’s Isolator webinar series, as they describe the various techniques used to quickly and safely move materials across barriers and into the final fill production space. Click here to register.


Next chapter in Isolator webinar series

On Wednesday, April 28th, the next chapter in Syntegon’s Isolator webinar series launches. Our experts Stefan Schuh, Dr. Laura Moody and Matthias Angelmaier will lead our free event, “How to handle complex isolator lines: Insights into the project life cycle of a liquid lyo-line”. Join them to learn more …more


Automated Capsule Product Development comes to the US at Syntegon’s Partner, Parsolex

Developing an oral solid dosage (OSD) product is not easy; timelines are long, financial risks are considerable and challenges are many. Consequently, significant incentive exists to find efficiencies and streamline the product development process wherever possible. However, one aspect of the pharma development process remains unchanged. Regulatory agencies are unwavering in their demand for evidence that your manufacturing process is stable and the design space well defined; …more


For effective moist heat terminal sterilization for large/small volume parenteral products, Syntegon delivers leading performance

Whenever feasible, regulatory agencies require injectable products to be terminally sterilized. Due to somewhat fragile molecules and compounds, this aseptic process may render the intended product to be adversely impacted and not endure the stress that moist-heat processes may subject them to. However, for those products that are more compatible to the heat and exposure, …more


Isolator webinar series continues!

You asked and Syntegon listened. Three new, free isolator-focused webinars are in the works, focused on crowdsourced topics that are important to you. Matthias Angelmaier, global product manager for barrier systems, isolator and process technology and Dr. Laura Moody, North American product manager for primary packaging, will keep the conversation going with a new variety of subjects: qualification & validation, project management of complex isolator lines and material transfer into barrier systems. On April 14th, …more


Facing the Challenges of Low Fill-Weight Capsules

Developing and manufacturing hard-shell capsules with low fill-weights can be an especially challenging task. However, recent innovations provide the tools to make the job of manufacturing such products much easier, while also providing assurance that the capsules you make meet your stringent quality requirements. Whether you need to fill just API into capsules for clinical trials, need to manufacture a low-fill capsule product for dry powder inhalation, or simply have a product formulation that requires low fill-weight, the tools available today can make the job much simpler. …more


Syntegon at the 2021 ISPE Aseptic Conference

Syntegon is pleased to be participating in two presentations at the upcoming 2021 ISPE Aseptic Conference, presented virtually March 15-17th. On Day 1,Global Product Manager for Isolator Technology Matthias Angelmaier will join speakers from Bavarian Nordic and IPS to discuss “Vaccines for the World – Insights into Design and Execution of a BSL2 Fill-Finish Facility”. Later that afternoon, …more


Login during lockdown – team spirit as a key success factor in digital times

COVID-19 is currently challenging our technical professionals in terms of traveling for set-ups and the commissioning of the delivered equipment to our customers worldwide. However, our customers are also suffering from travel restrictions, which make it difficult to carry out a joint Factory Acceptance Tests (FAT) on the manufacturer’s site. A FAT is a process to approve that the equipment aligns with the specifications made for design and functions, before it is dispatched to our customers.

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