UX-based redesign KHD 2000 – off-line Glove Testing System

Barrier systems such as isolators or RABS play a fundamental role in the protection of people and products in pharmaceutical production. Only tenths of a millimeter thick gloves are the most crucial interface in these hermetically sealed units. To ensure that barrier systems are sterile, and processes remain safe, a thorough and regular inspection of the glove integrity is vital. The regulatory requirements for gloves are strict. However, they also leave plenty of choice for suitable test methods. Many facility operators face the question as to which method is suited best for which system.

 

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Explore Assembly and Labeling solutions for medical devices

Self-administration of drugs is on the rise – due to the increase in lifestyle-related diseases, as well as major advances in oncology and hormone therapy. Thanks to the availability of devices to support self-administration of drugs, todays patients can manage their own treatment, more independently than ever before.

Following this trend, pharmaceutical companies are increasing the availability of combination products. In order to fulfill the growing demand …more


A flexible leader in cartridge processing

Here’s one for the books: with almost 50 years of experience, we are the world market leader in cartridge processing. On all five continents, more than 200 Syntegon filling machines ensure safe and flexible filling of liquid pharmaceuticals into cartridges – regardless of container size and output rate.

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Capsylon Capsule Fillers: The Benchmark for Cost-Effective Capsule Filling

For decades, Syntegon Pharma Technology has set the standard in capsule filling technology for the Pharmaceutical industry. Pharma manufacturing experts seeking innovation, durability and maximum filling flexibility have intuitively turned to the Syntegon line of GKF capsule fillers. With a variety of filling options including powder-fill, pellet-fill, tablets-in-capsule, or any variety of filling combinations, the GKF line of capsule fillers can tackle any capsule filling challenge thrown at them.

But, what if your capsule filling needs are more simple? …more


BIOGRUND and Syntegon Partner to Make Your Life Easier

In many of my previous Syntegon articles, I have lamented the high cost of drug product development, with good reason. Developing an oral-solid-dose drug product is an expensive and risky endeavor, with formulation and process development being among the most significant and time consuming challenges.

It is no secret that formulation scientists face a host of hurdles when developing a formulation bound for tablet compression. First and foremost is achieving …more


Successful Versynta small batch event

Last week, Syntegon hosted the Versynta Small Batch Event, opening the virtual doors to the Crailsheim production plant for attendees from around the world. During the event, external speakers from IPS, Valicare and Ferring GmbH shared their expertise related to the growing small batch pharma field. A live, detailed demonstration of the Versynta Flexible Filling Platform (FFP) followed, highlighting the individually configurable and flexible machine for filling aseptic and high potent liquid active ingredients. The showcase concluded with …more


Take your molecule to production

Compromise no longer; Syntegon’s GKF 60 R&D capsule filler is here! The GKF 60 combines a small machine footprint with the durability, innovation and flexibility you have grown to expect from Syntegon.  When designing the GKF 60, our mission was simple, “design it to do everything.” We think you will agree that it does exactly that.

In the OSD product development world there a few hard and fast rules; plans change; timelines shrink; and API is scarce. That is where the flexibility of the GKF 60 comes in. …more


Syntegon’s Slide Gate Technology Improves Capsule Filling Performance

Although Syntegon’s tamping-style capsule filling machines have set the standard for precision and durability in capsule filling for decades, that does not mean we rest on our laurels. At Syntegon, we tirelessly pursue innovations that make our industry leading equipment even better.  One of the most important of those innovations to come out of Syntegon’s Waiblingen, Germany facility in recent years is slide gate technology for capsule fillers. …more


Syntegon’s Pilot Scale High-Shear Mixer and Fluid Bed

Developing a pharmaceutical product within a Research and Development Lab can be a very expensive and time-consuming process for OSD manufacturers. Once a stable product has been developed within the lab setting, scaling up to pilot production can prove even more daunting for scientists. Pilot-scale machines provide pharmaceutical companies the tools to better understand a manufacturing process that was successful at lab scale, while also allowing for batches at less than production scale, where design changes can still be easily executed at less cost. Syntegon offers …more


How do I get my materials into an Isolator?

Fill/finish lines surrounded by RABS and/or Isolators come with many benefits, but one of the initial challenges is determining how to transfer commodities, fluid paths, tools or drug product itself into the closed ISO 5 space. Have no fear, Syntegon’s experts are here! Join Matthias Angelmaier and Dr. Laura Moody on Wednesday, May 12th at 10am CDT for the final chapter in Syntegon’s Isolator webinar series, as they describe the various techniques used to quickly and safely move materials across barriers and into the final fill production space. Click here to register.


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