Fluid bed processing has long been used in the Pharmaceutical, Nutraceutical, and Chemical industries as a way to enhance the characteristics of powders, dry products, or apply an active compound or functional coating to the surface of particles or beads, with the objective of controlling release of the product. …more
The pharmaceutical and nutraceutical industries are constantly looking for ways to develop robust and efficient processes across their oral solid dosage (OSD) portfolios. Producing a quality tablet or capsule should start much earlier than when the tablet press or capsule hopper is filled with powder or granules. …more
Syntegon Technology may not be a household name to many people, but if you have worked in oral solid dosage manufacturing for any length of time, you are likely very familiar with our capsule filling machines. That’s because just over one year ago Bosch Packaging Technology, a name synonymous with capsule filling, became Syntegon Technology, a fully independent provider of processing equipment for the pharmaceutical, nutraceutical and food industries. And in our first year as an independent company …more
Developing a capsule or tablet product is fraught with hurdles, both financial and technical. Traditional process development generally involves what seems like an endless cycle of batch manufacture, followed by testing/characterization, followed by more batch manufacture and even more testing. Execution of just one simple Design of Experiments (DOE) could easily take several days, if not weeks, only to be followed by additional batches. …more
Taking a look back at 2020, everyone will most likely agree we have experienced many new ways to conduct business both personally and professionally. For Syntegon Technology, 2020 was officially the first year we conducted business as a separate and independent entity from what we were formerly known as, which was Bosch Packaging Technology. Syntegon Technology became the new name and face for a leading provider of processing and packaging solutions for the food and pharmaceutical industries. Syntegon has …more
Scale it up quicker and do it more efficiently (i.e. less cost). If you work in pharmaceutical development, you are likely familiar with this mantra. While regulatory hurdles for drug developers seemingly increase by the day, product development budgets don’t seem to follow the same upward trajectory. In fact, it seems that development and manufacturing personnel, more often than not, are asked to do more with less. …more
Syntegon’s Oral Solid Dosage product line continues to advance and offer unsurpassed technologies and innovation for our customers and their manufacturing needs. Our newest product offering comes in the form of a drum coater that we call, Sepion. The Sepion builds on decades of expertise from …more
With pharmaceutical companies increasing development of highly potent drugs, manufacturers of those drug products, both innovator companies and contract manufacturers alike, continue to seek better contained manufacturing equipment to ensure protection of both personnel and products.
While potent drug products come in a variety of dosage forms and potencies, …more
Syntegon Pharma Technology is pleased to announce the completion of a major capital investment program with our partners, Parsolex GMP Center. This investment consists of the installation of multiple pieces of equipment to enhance Parsolex’s existing analytical, development and cGMP manufacturing capabilities. The upgraded facility includes …more
Continuous Manufacturing has steadily gained momentum within the Oral Solid Dosage (OSD) industry over the last handful of years. Seeking significantly faster product development, reduced production costs, and higher yields, many pharmaceutical companies have made a concerted effort to implement continuous manufacturing lines within their production facilities. Continuous Manufacturing can allow inefficient batch processing to be a relic of the past, being replaced with smart sensing technology and unsurpassed product quality. …more
