Solid Dosage

Syntegon’s Slide Gate Technology Improves Capsule Filling Performance

Although Syntegon’s tamping-style capsule filling machines have set the standard for precision and durability in capsule filling for decades, that does not mean we rest on our laurels. At Syntegon, we tirelessly pursue innovations that make our industry leading equipment even better.  One of the most important of those innovations to come out of Syntegon’s Waiblingen, Germany facility in recent years is slide gate technology for capsule fillers. …more


Syntegon’s Pilot Scale High-Shear Mixer and Fluid Bed

Developing a pharmaceutical product within a Research and Development Lab can be a very expensive and time-consuming process for OSD manufacturers. Once a stable product has been developed within the lab setting, scaling up to pilot production can prove even more daunting for scientists. Pilot-scale machines provide pharmaceutical companies the tools to better understand a manufacturing process that was successful at lab scale, while also allowing for batches at less than production scale, where design changes can still be easily executed at less cost. Syntegon offers …more


Join Syntegon at the 2021 Virtual Pharma Expo

Join Syntegon at the 2021 Virtual Pharma Expo series event, focused on Oral Solid Dose Manufacturing. On Wednesday, May 5 at 9:30am EDT, Head of Pharma Service and Senior Scientist/Pharmacist Marc Michaelis will be presenting on Continuous Manufacturing. Learn about the benefits of moving from batch production to a continuous process.

Learn more about the event, and register for free here.


Automated Capsule Product Development comes to the US at Syntegon’s Partner, Parsolex

Developing an oral solid dosage (OSD) product is not easy; timelines are long, financial risks are considerable and challenges are many. Consequently, significant incentive exists to find efficiencies and streamline the product development process wherever possible. However, one aspect of the pharma development process remains unchanged. Regulatory agencies are unwavering in their demand for evidence that your manufacturing process is stable and the design space well defined; …more


Facing the Challenges of Low Fill-Weight Capsules

Developing and manufacturing hard-shell capsules with low fill-weights can be an especially challenging task. However, recent innovations provide the tools to make the job of manufacturing such products much easier, while also providing assurance that the capsules you make meet your stringent quality requirements. Whether you need to fill just API into capsules for clinical trials, need to manufacture a low-fill capsule product for dry powder inhalation, or simply have a product formulation that requires low fill-weight, the tools available today can make the job much simpler. …more


Login during lockdown – team spirit as a key success factor in digital times

COVID-19 is currently challenging our technical professionals in terms of traveling for set-ups and the commissioning of the delivered equipment to our customers worldwide. However, our customers are also suffering from travel restrictions, which make it difficult to carry out a joint Factory Acceptance Tests (FAT) on the manufacturer’s site. A FAT is a process to approve that the equipment aligns with the specifications made for design and functions, before it is dispatched to our customers.

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Syntegon Technology: The Capsule Filling Experts

Syntegon Technology may not be a household name to many people, but if you have worked in oral solid dosage manufacturing for any length of time, you are likely very familiar with our capsule filling machines. That’s because just over one year ago Bosch Packaging Technology, a name synonymous with capsule filling, became Syntegon Technology, a fully independent provider of processing equipment for the pharmaceutical, nutraceutical and food industries. And in our first year as an independent company …more


Accelerating Product Development: Don’t Go-It Alone

Developing a capsule or tablet product is fraught with hurdles, both financial and technical. Traditional process development generally involves what seems like an endless cycle of batch manufacture, followed by testing/characterization, followed by more batch manufacture and even more testing. Execution of just one simple Design of Experiments (DOE) could easily take several days, if not weeks, only to be followed by additional batches. …more


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