Vaccines 101 and Syntegon’s Fill-Finish Portfolio

In the midst of our current, ever-changing worldwide coronavirus crisis, the word on everyone’s mind is vaccine.  Never before have the world’s scientific and pharmaceutical communities felt such a collective rush to bring life-saving vaccines to market. In today’s post, our resident filling systems and single-use technology expert, Dr. Laura Moody, provides an overview of the different types of vaccines, how they work, and how Syntegon’s fill-finish portfolio supports clinical and commercial manufacturing.

 

The intention behind a vaccine is to train the body’s immune cells …more



Syntegon Delivers 16th and 17th Model FLT Small Batch Vial Filler for ATMPs

FLT #16 configured to fill gene therapy products in an isolator

 

The Minneapolis plant of Syntegon is proud to announce the delivery of its 16th and 17th model FLT small batch vial filler for ATMP applications. Configured to fill gene therapy products in an isolator and oncolytic immunotherapies and vaccines in a RABS, respectively, these latest deliveries of the proven FLT platform for RTU vials exemplify the trend towards smaller batches of higher value products and highlight Syntegon’s track record of providing solutions that meet the exacting requirements of the rapidly growing ATMP segment.

The Syntegon FLT vial filler is designed …more


Russian regulatory against counterfeiting of cosmetic products

By end of December 2019, the Russian government published regulatory guidelines regarding Track & Trace for cosmetic products. Aim is to inform and protect customers from counterfeits. Since the deadlines are quite close, we have set up all information regarding necessary activities and the ways of implementing in time. …more


ADCs & state-of-the-art fill-finish technology (for high potent drugs)

These days people are talking a lot about cell/gene therapy drugs, clinical trials, monoclonal antibodies and other exciting topics around small batch fill-finish solutions. Syntegon provides robust and sustainable solutions at an affordable price for every business size. There are solutions for clinical trials, small batch applications, and higher output rates.

There´s a growing demand for small batch production for ADC products (Antibody Drug Conjugates). The operator safety and the best possible protection for these types of drugs is crucial. Syntegon’s approach is …more


Technical Audits: Getting a check-up from head to toe

Just like we human beings, production equipment also needs a health check-up every now and then, performed by a team of specialist “doctors”.

Whether it is the output or scrap rate, set-up or handling time – packaging and processing lines have many areas where subtle problems can hide. But once a problem is recognized, how is the manufacturer to identify these hidden issues without disassembling the entire line?

We have got the answer: a “technical audit”.

…more


Glove Testing Systems – The highest safety for isolators and RABS

Barrier systems such as isolators or RABS play a fundamental role in the protection of people and products in pharmaceutical production. Only tenths of a millimeter thick gloves are the most crucial interface in these hermetically sealed units. To ensure that barrier systems are sterile, and processes remain safe, a thorough and regular inspection of the glove integrity is vital. The regulatory requirements for gloves are strict. However, they also leave plenty of choice for suitable test methods. Many facility operators face the question as to which method is suited best for which system.

…more



Auto-injector assembly: Flexible and scalable production is key

Self-administration of drugs on the rise

PCI Pharma Services relies on RRA assembly machine from Bosch Packaging Technology

The injectable drug delivery market has experienced a huge change in recent years. Due to drastic changes in lifestyle and the accompanying increase in chronic diseases such as diabetes, the demand for injectable drugs has been growing for decades. This transformation relates not only to the quantity, but also to the way in which injectable drugs are delivered today.

…more


Top of page